anal fistula
Conditions
Interventions
Control group:Routine dressing changes
Test group:Take Lianqi Pills orally
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Meet the western medical diagnostic criteria of inter-sphincteric anal fistula and the Chinese medical diagnostic criteria of anal fistula with syndrome of dampness-heat diffusing downward; (2) Age =18 years old and =65 years old gender is not limited; (3) intend to undergo transanal opening of intersphincteric space in our hospital without contraindications to surgery; (4) Knowing and agreeing to participate in this study willing to receive treatment according to the requirements regular follow-up and not practical any drugs that may affect postoperative wound healing during the treatment period and signing the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Combined with hematopoietic and coagulation disorders; (2) Those with a combination of serious cardiovascular cerebrovascular and hepatic or renal diseases or uncontrolled metabolic diseases; (3) Those with the combination of tuberculosis tumor inflammatory bowel disease or other diseases that may affect postoperative wound healing; (4) Those who have a recent need to prepare for pregnancy or are in the period of pregnancy or breastfeeding; (5) Those who have uncontrolled mental illnesses and cannot cooperate with the whole process during the treatment; (6) Those who are allergic to the drugs used in this study; (7) Participating in other clinical studies at the same time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The postoperative wound healing rate in the first month; | — |
Secondary
| Measure | Time frame |
|---|---|
| Macrophage polarization in wound tissue;Recurrence rate;Wound healing time;Postoperative wound inflammatory factors;Detection of 16sr RNA of wound microbiota;Wound evaluation tool score for improved wound images; | — |
Countries
China
Contacts
Public ContactZhenyi Wang
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed