Frailty
Conditions
Interventions
Healthy control group:no
Tai Chi Group:24-form Simplified Tai Chi Chuan
Health Education Group:Health Education
Sponsors
Fujian Provincial Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for frail patients: 1)Age: =65 years old; 2) Meet at least 3 of the Fried frailty phenotypes: (1) Weight loss: Weight loss > 3 kg in the past half year (excluding dieting or exercise); (2) Low grip strength: Men 173 cm or for women with a height > 159 cm the walking speed is =0.76 m/s;) Male with a height of =173 cm or female with a height of =159 cm and a walking speed of =0.65m/s; (5) Decreased physical activity: The activity level in one week was <600 MET-min/ week (evaluated using the International Physical Activity Questionnaire Short Form (IPAQ-SF)); 3) The Mini-Mental State Examination (MMSE) score is =24 points and severe cognitive impairment is excluded. 4) Be capable of walking independently (without the need for auxiliary equipment) and complete gait tests; 5) Sign the informed consent form: Voluntarily participate in the research and sign the informed consent form. Only those meeting all the above five criteria can be included in the research project. Inclusion criteria for healthy volunteers: 1)Age: =65 years old; 2) Conform to the Fried frailty phenotype < 1 item; 3) The Mini-Mental State Examination (MMSE) score is =24 points and severe cognitive impairment is excluded. Athletic ability 4) Be able to walk independently (without auxiliary equipment) completed 5) Sign the informed consent form: Voluntarily participate in the research and sign the informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1) Severe neurological diseases: such as stroke Parkinson's disease Alzheimer's disease etc. 2) Severe motor system diseases: such as rheumatoid arthritis severe osteoporosis etc. which affect athletic ability; 3) Contraindications for MRI: such as implantation of metal devices in the body claustrophobia etc. 4) Severe cardiovascular diseases: such as unstable angina pectoris and recent myocardial infarction etc. are not suitable for exercise intervention. 5) Recent participation in other sports interventions: Regularly participated in Tai Chi or other sports training within the past six months; 6) Others: Severe mental disorders (such as major depression schizophrenia); 7) Malignant tumors or other serious chronic diseases; 8) Unable to cooperate in completing the research process.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Berg Balance Scale (BBS);Short Physical Performance Battery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gait biomechanics;surface emg;Resting-state functional magnetic resonance imaging(fMRI);Neuro-biomechanical mechanism coupling;Performance of fall risk prediction model;MoCA; | — |
Countries
China
Contacts
Public ContactLin ZhongHua
Fujian Provincial Hospital
Outcome results
None listed