moderate Depression
Conditions
Interventions
Sham acupuncture group:The sham Tiaoshenguben Acupuncture
Acupuncture group:Tiaoshenguben Acupuncture
Healthy control group:none
Sponsors
Bao'an District Traditional Chinese Medicine Hospital Bao'an District Shenzhen City
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: For the depression patients: (1) Pregnant women; (2) Patients combined with severe primary diseases of the heart brain liver kidney and hematopoietic system; (3) Patients with acute diseases infectious diseases or malignant tumors; (4) Patients with a history of schizophrenia or other mental illnesses; (5) Patients with cognitive disorders or personality disorders; (6) Individuals with severe suicidal ideation or suicidal behavior; (7) Patients with organic brain damage (e.g. epilepsy) or other diseases involving paroxysmal brain electrical discharges; (8) Individuals who have undergone electroconvulsive therapy (ECT) or transcranial magnetic stimulation (TMS) within the recent 3 months; (9) Individuals with HAMD-17 score > 23; (10) Participants involved in the MRI substudy but having MRI contraindications or failing to meet quality control requirements. Healthy controls: (1) Sex age years of education comparable to the patient group; (2) HAMD-17 and Pittsburgh Sleep Quality Index (PSQI) total scores both < 7; (3) No severe mental illnesses and physical diseases; (4) Right-handed; (5) No metal implants in the body and no claustrophobia. For the healthy controls: (1) Sex age years of education comparable to the patient group;(2) HAMD-17 and Pittsburgh Sleep Quality Index (PSQI) total scores both < 7; (3) No severe mental illnesses and physical diseases; (4) Right-handed; (5) No metal implants in the body and no claustrophobia.
Exclusion criteria
Exclusion criteria: (1) Pregnant women; (2) Patients combined with severe primary diseases of the heart brain liver kidney and hematopoietic system; (3) Patients with acute diseases infectious diseases or malignant tumors; (4) Patients with a history of schizophrenia or other mental illnesses; (5) Patients with cognitive disorders or personality disorders; (6) Individuals with severe suicidal ideation or suicidal behavior; (7) Patients with organic brain damage (e.g. epilepsy) or other diseases involving paroxysmal brain electrical discharges; (8) Individuals who have undergone electroconvulsive therapy (ECT) or transcranial magnetic stimulation (TMS) within the recent 3 months; (9) Individuals with HAMD-17 score > 23; (10) Participants involved in the MRI substudy but having MRI contraindications or failing to meet quality control requirements. Healthy controls: (1) Accompanied by psychotic symptoms; (2) Females in pregnancy lactation period or with planned pregnancy; (3) Alcohol or substance abuse; (4) History of organic brain lesions and brain injury; (5) Existence of any history of mental illnesses or neurological diseases; (6) Patients combined with severe primary diseases of the heart brain liver kidney and hematopoietic system; (7) Recent suicidal behavior or obvious suicidal tendencies; (8) Participants involved in the MRI substudy but having magnetic resonance imaging (MRI) scanning contraindications or being unable to meet quality control requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The reduction rate of HAMD-17; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index;Insomnia Severity Index;Hamilton Anxiety Scale;functional magnetic resonance imaging;Self-Rating Depression Scale;17-item Hamilton Depression Scale;Ruminative Response Scale;36-item Short-Form Health Survey;Electroencephalogram;Trail Making Test; | — |
Countries
China
Contacts
Public ContactPeng Zhou
Bao'an District Traditional Chinese Medicine Hospital No. 25 Yu'an 2nd Road Bao'an District Shenzhen City Guangdong Province
Outcome results
None listed