Acute pulmonary thromboembolism
Conditions
Interventions
Western Medicine Group:Anticoagulation therapy
Integrated Traditional Chinese and Western Medicine Group:Yifei Tiaoxue Formula Instant Granules combined with anticoagulation therapy
Sponsors
China-Japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1) Age =18 years; (2) Diagnosed with acute pulmonary thromboembolism (PTE) with or without deep vein thrombosis (DVT); (3) Non-high-risk stratification of PTE; (4) According to the Guidelines for the Diagnosis Treatment and Prevention of Pulmonary Thromboembolism presence of at least one of the following high-risk bleeding factors: age >75 years; history of stroke within the past 3 months; history of surgery within the past 3 months; malignancy; thrombocytopenia; diabetes mellitus; anemia; or current antiplatelet therapy; (5) Syndrome of qi deficiency and blood stasis (traditional Chinese medicine diagnosis); (6) Cumulative use of anticoagulants or Qi-invigorating and blood-activating herbal formulas for no more than 3 days within the 30 days prior to baseline; (7) Voluntary participation in the study with signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients requiring anticoagulation with warfarin; (2) Concomitant liver or kidney dysfunction (any one of ALT AST Scr or BUN exceeding the upper limit of normal reference values); (3) Severe diseases of the digestive nervous hematologic or cardiocerebrovascular systems or severe mental disorders; (4) Having undergone thrombolytic therapy interventional procedures or surgical treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Residual Thrombus;Bleeding Event; | — |
Secondary
| Measure | Time frame |
|---|---|
| VTE Recurrence;All-Cause Mortality;VTE-Related Mortality;Quality of Life Score (PEmb-QoL); | — |
Countries
China
Contacts
Public ContactDemin Li
China-Japan Friendship Hospital
Outcome results
None listed