Oligoasthenospermia
Conditions
Interventions
Treatment group:Jianpi Yishen Shengjing Formula combined with Levocarnitine oral solution
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Wesitern Medicine, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Male
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1.Men who meet the Western medical diagnostic criteria for oligoasthenospermia; 2.Individuals who are diagnosed with spleen-kidney deficiency syndrome according to traditional Chinese medicine (TCM) standards for oligoasthenospermia; 3.Males aged between 20 and 45 years old with a desire for fertility; 4.Participants who have not taken medications that could affect the study outcomes within the three months prior to enrollment, such as finasteride, methotrexate, cyclophosphamide, cimetidine, etc.; 5.Individuals with normal sexual function, and no definitive etiology identified through a comprehensive baseline examination of relevant systemic indicators and a specialized examination of the urogenital system; 6.Those who understand and agree to participate in this study and have signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Individuals with abnormal chromosomal tests or endocrine examinations; 2.Patients with azoospermia or organic lesions of the reproductive organs; 3.Those with abnormal diseases of the cardiovascular, hepatorenal systems, or hematopoietic functions; 4.Individuals with diseases that may affect semen quality, such as acute prostatitis, epididymal tuberculosis, cryptorchidism, varicocele, etc.; 5.People with allergic constitution or hypersensitivity to the medication, as well as those with impaired liver or kidney functions; 6.Patients with poor habits that significantly affect semen quality and those with psychiatric disorders (such as long-term alcohol consumption, smoking, staying up late, sauna bathing, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of Progressive Motile Sperm; | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage of Normal Morphology Sperm;Cumulative Pregnancy Rate;sex hormone levels;Total Motility Rate of Sperm;Total Sperm Count;Semen Volume;Sperm Concentration;Syndrome Score Scale of Traditional Chinese Medicine; | — |
Countries
China
Contacts
Public ContactYu Peng
Yueyang Hospital of Integrated Traditional Chinese and Wesitern Medicine, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed