IgA nephropathy
Conditions
Interventions
Control group:Chaiqin Formula Placebo and supportive care
Intervention group:Chaiqin Formula and supportive care
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age = 18 years old and = 75 years old gender not limited; (2) Renal biopsy diagnosed IgAN; (3) eGFR-EPI =50mL/min/1.73m2 (4) Urinary protein: 0.5g-3.0g/24h; (5) Agree and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Renal biopsy suggested crescent IgAN or requires immunosuppressive therapy; (2) Secondary IgAN such as IgA vasculitis liver disease autoimmune diseases tumors etc; (3) Application of antibiotics or intestinal regulating drugs such as laxatives and probiotics within the past 4 weeks; (4) Individuals who have participated or are currently participating in other clinical trials within the past month prior to participating in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ?Clinical Response Rate??; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fecal metabolomics analysis;Quantitative Urine Protein??;serum BAFF;gut microflora analysis using 16S rRNA;serum APRIL;Urinalysis;serum Gd-IgA1;Renal function; | — |
Countries
China
Contacts
Public ContactYi Wang
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed