Oligoasthenospermia
Conditions
Interventions
Asthenospermia Control group:Shengjing Capsules Simulation Agent+Compound Xuanju Capsule
Asthenospermia Experimental group:Shengjing Capsules +Compound Xuanju Capsule Simulation Agent
Oligozoospermia Control group:Shengjing Capsules Simulation Agent+Compound Xuanju Capsule
Oligozoospermia Experimental group:Shengjing Capsules +Compound Xuanju Capsule Simulation Agent
Sponsors
Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University
Eligibility
Sex/Gender
Male
Age
22 Years to 50 Years
Inclusion criteria
Inclusion criteria: (1)Male aged 22 to 50 (inclusive); (2) Patients who meet at least one of the diagnostic criteria of male Oligozoospermia or Asthenospermia in western medicine; (3) Patients who meet the diagnostic criteria for ShenYang deficiency syndrome in traditional Chinese medicine; (4) Voluntarily sign the informed consent form
Exclusion criteria
Exclusion criteria: (1) There are gonadal dysplasia, hypogonadism, testicular atrophy, cryptorchidism, chronic epididymitis, and retrograde Ejaculation or no ejaculation, Y chromosome microdeletion, grade II or above varicocele, urinary tract infection, acute patients with diseases such as seminal vesiculitis and acute prostatitis; (2) Patients with a history of reproductive organ surgery or trauma that affects their reproductive function; (3) Those who take anti-epileptic, anti-tumor or other drugs that may hinder sperm production and sperm motility, etc. (4) Patients with abnormal sex hormones that have clinical significance; (5) There are serious primary diseases of the heart, liver, kidneys, hematopoietic system, endocrine system, respiratory system, etc. Patients with liver function ALT and/or AST higher than the upper limit of the reference value by more than 1.5 times, and renal function Scr higher than the upper limit of the normal value; (6) Combined with hypertension (Patients with persistent hypertension with systolic blood pressure >185mmHg or diastolic blood pressure>110mmHg after antihypertensive treatment) and patients with poor blood sugar control (glycosylated hemoglobin >7.5%),Patients with obesity (BMI=27) or accompanied by metabolic syndrome; (7) Having a long-term and excessive habit of smoking and drinking, or being exposed to high-temperature, radioactive or toxic chemical environments, but not Patients who can change or give up; (8) People with allergic constitutions, or those known to be allergic to the test drug and its components; (9) Patients with intellectual disabilities, mental disorders, etc., who may affect the evaluation of the trial; (10)Patients who are currently participating in other clinical trials or have participated in other drug clinical trials and have completed them within less than 3 months; (11)Patients with other conditions that the researcher deems inappropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sperm concentration;Percentage of sperm forward movement; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sperm concentration;Percentage of sperm forward movement;Total sperm count;Sperm survival rate and sperm motility;Total score of TCM syndromes and individual symptom scores;Efficacy of Traditional Chinese Medicine Syndromes; | — |
Countries
China
Contacts
Public ContactLiancheng Jia
Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University
Outcome results
None listed