post-infectious cough
Conditions
Interventions
Cough Plaster Group:Cough Plaster 1 piece each time, once a day, applied to the Tian Tu acupoint, for use at night.
Sponsors
Dongzhimen Hospital Beijing University of Chinese Medicine Beijing 100700 China
Eligibility
Sex/Gender
All
Age
No minimum to 99 Years
Inclusion criteria
Inclusion criteria: 1) Meet the diagnostic criteria for post-infectious cough; 2) Meet the traditional Chinese medicine diagnostic criteria of pattern of wind-cold invading the lung; 3) Duration of the disease is 3~6 weeks; 4) No restrictions of gender and age; 5) Volunteer to be tested and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) Cough caused by the following diseases such as chronic bronchitis bronchial asthma bronchiectasis tracheo-bronchial tuberculosis cough variant asthma eosinophilic bronchitis postnasal drip syndrome gastro-esophageal reflux cough psychogenic cough and pertussis; 2) Combination of active tuberculosis lung infection chronic obstructive pulmonary disease or other lung diseases (e.g. pulmonary embolism interstitial lung disease etc.); 3) Combined cardiovascular system diseases (including but not limited to: cardiac arrhythmia such as atrial fibrillation frequent atrial premature beats and ventricular premature beats etc.) neurological blood and hematopoietic system and other important organs and systems with serious primary diseases as well as combined with psychiatric disorders etc. and can not cooperate; 4) Those with systolic blood pressure =160 mmHg and/or diastolic blood pressure =100 mmHg after standardized treatment measured in the resting (at least 10 minutes) state at screening; 5) Patients with symptoms of irritating dry cough due to oral administration of drugs such as ACEIs; 6) Temperature of 37.3°C and above or elevated leukocytes (> 1.2 ULN); 7) Abnormal results of laboratory tests of liver and renal function during the screening period: ALT AST > 1.5 ULN Cr > ULN; 8) Pregnant or preparing for pregnancy and lactating women; 9) Those with severe gastrointestinal disorders or those who have undergone gastrointestinal surgery that in the judgment of the investigator may interfere with drug absorption; 10)Patients with malignant tumors; 11)Persons with allergies or those who are allergic to the components of the drugs used in this test; 12) Those who have consumed alcohol in excess (more than 21 units of alcohol per week 1 unit = 8g or 10mL of pure alcohol) in the 3 months prior to screening and who are unable to stop consuming alcohol during the course of using the drug; 13) Those who have used other Chinese or Western medicines or treatments (e.g. acupressure acupuncture etc.) for the treatment of the disease within 72 hours before using the test drug; 14) Subjects who have participated in clinical trials of other drugs/devices in the last 1 month; 15) Subjects judged by the investigator to have poor adherence or any other inappropriate for participation in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cough disappearance rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cough disappearance time;Cough numerical rating scale;Cough Evaluation Test CET;Leicester Cough Questionnaire (LCQ);Disappearance rate of single symptom;Curative effect of TCM syndrome; | — |
Countries
China
Contacts
Public ContactShengxian Wu
Dongzhimen Hospital Beijing University of Chinese Medicine Beijing 100700 China
Outcome results
None listed