Infectious Mononucleosis in children
Conditions
Interventions
Test group:Ganciclovir intravenous drip therapy combined with Chinese traditional medicine(Ding shi san yang tou jie decoction)
Control group:Ganciclovir intravenous drip
Sponsors
The First Affiliated Hospital of Henan University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
1 Years to 14 Years
Inclusion criteria
Inclusion criteria: (1) Meets the western clinical diagnostic criteria or laboratory confirmation criteria for IM in children; (2) The TCM diagnosis is sanyangrechi syndrome; (3) The age of the child is 1 to 14 years old; (4) Parents of the child signed an informed consent form and were able to adhere to medication and regular follow-up appointments; (5)No serious cardiac cerebral renal circulatory or neurological damage and able to adhere to the medication and regular follow-up.
Exclusion criteria
Exclusion criteria: (1) Contraindications to ganciclovir administration or hypersensitivity to known constituents of herbal preparations; (2) Serious complications during the course of the disease such as phagocytic syndrome splenic rupture and meningitis; (3) Having been treated with antiviral drugs or other herbal formulas within one week prior to treatment; (4) Those who cannot use the medication as prescribed or have incomplete information etc. which affects the judgment of efficacy and safety.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to complete antipyretic;Disease Efficacy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of heterogeneous lymphocytes;Peripheral blood lymphocyte ratio;T-lymphocyte subset;Scoring of major clinical symptoms and signs;EBV-DNA load;Chinese Medicine Symptoms; | — |
Countries
china
Contacts
Public ContactYongbin YAN
The First Affiliated Hospital of Henan University of Traditional Chinese Medicine
Outcome results
None listed