lupus nephritis
Conditions
Interventions
active group:Metabolomics testing
Remission Phase Group:Metabolomics testing
Healthy control group:Metabolomics testing
Sponsors
Tongde Hospital of Zhejiang Province
Eligibility
Sex/Gender
All
Age
16 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Ages ranging from 16 to 65 years old with no restrictions on gender or ethnicity; 2.LN patients who fulfill the diagnostic criteria outlined in the 2012 ACR/EULAR guidelines; 3.Patients demonstrating good clinical compliance; 4.Individuals who voluntarily agree to participate in this study and have signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients with multiple infections; tumors and severe damage to vital organs; 2.Patients with infectious diseases such as typhoid fever; tuberculosis; hepatitis B and others; 3.Patients diagnosed with other immune disorders; including dermatomyositis; allergic purpura; rheumatoid arthritis; Sjogren's syndrome etc; 4.Patients with severe renal impairment who are undergoing dialysis treatment; 5.Pregnant or lactating women; 6.Patients for whom clinical data cannot be collected.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood and urine metabolites; | — |
Secondary
| Measure | Time frame |
|---|---|
| hemoglobin;immunoglobulin;urinary protein;BILAG-2004 Integral;Blood creatinine;Traditional Chinese Medicine Syndrome Integral;antinuclear antibodies;white blood cells;urinary RBC;SLEDAI Integral;blood urea nitrogen;Glomerular Filtration Rate;Alanine aminotransferase;Aspartate aminotransferase;seralbumin;platelet;complement; | — |
Countries
China
Contacts
Public ContactXiaoqian Yan
Tongde Hospital of Zhejiang Province
Outcome results
None listed