Ulcerative Colitis
Conditions
Interventions
Experimental group:Kuijie Core Formula + mesalazine
Sponsors
Shuguang Hospital Affiliated to Shanghai University of traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1)Underwent electronic colonoscopy within the past 3 months and met the diagnostic criteria for UC with the Large Intestine Dampness-Heat Pattern. (2)No gender restriction; aged 18–70 years with no history of intestinal surgery. (3)In the active phase of ulcerative colitis with a Mayo score of 3–12 points. (4)Good patient compliance able to understand the study details and provide informed consent approved by the hospital's ethics committee.
Exclusion criteria
Exclusion criteria: (1)Patients with infectious colitis such as intestinal tuberculosis bacterial dysentery etc. (2)Patients with complications requiring surgical treatment such as intestinal perforation intestinal obstruction intestinal stenosis or malignancy . (3)Pregnant or breastfeeding women. (4)Patients with severe acute or chronic diseases such as acute myocardial infarction acute pancreatitis stroke heart failure Lynch syndrome malignancies etc. . (5)Patients with allergic constitution or known allergies to the components of the study medication. (6)Patients with language or intellectual disabilities or other reasons that may prevent cooperation with the study and follow-up. (7)Patients currently participating in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Efficacy Evaluation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Mayo Score;IBDQ;Inflammatory-Related Factors;Intestinal Mucosal Barrier;Intestinal Mucosal Healing Rate;Efficacy Evaluation of Traditional Chinese Medicine (TCM) Syndromes;C-Reactive Protein to Albumin Ratio (CAR); | — |
Countries
China
Contacts
Public ContactYang Wei
Shuguang Hospital Affiliated with Shanghai University of traditional Chinese Medicine
Outcome results
None listed