Addiction to Amphetamine type Substances
Conditions
Interventions
Sponsors
The Third Affiliated Hospital of Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Diagnostic criteria for ATS addiction Based on the latest Diagnostic Manual DSM-5 of the American Psychiatric Association the specific diagnostic criteria for ATS withdrawal are as follows: 1) Stop or reduce long-term use of ATS; 2) If two or more of the following symptoms occur while meeting the first condition: a Fatigue; b Unpleasant dreams; C Excessive sleep or insomnia; d Increased appetite; e Psychomotor irritability or retardation 3) The above symptoms cause pain or significant damage to the patient's profession or other important areas; 4) The above symptoms and signs cannot be attributed to other physical illnesses nor can they be better explained by other mental disorders including poisoning or withdrawal from other substances; (2) Inclusion criteria 1) Meets the diagnostic criteria for ATS withdrawal symptoms; 2) History of positive urine test for methamphetamine; 3) Age range: 18-60 years old both male and female with clear consciousness no aphasia or intellectual disabilities education level of primary school or above able to understand the content of the scale and cooperate with treatment; 4) MoCA scores less than 26 with subjects with less than 12 years of education receiving an additional score of 1; 5) Not participating in other clinical trials within 3 months; 6) Sign the informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria 1) Local trauma and infection patients receiving TEAS treatment; 2) Individuals who cannot tolerate electrical stimulation or are allergic to rubber products or alcohol; 3) Pregnant and lactating women; 4) Has severe heart liver kidney dysfunction or suicidal tendencies; 5) Previous history of organic brain diseases or other neurological disorders that affect cognitive function or history of traumatic brain injury or coma; 6) According to the researcher's judgment it is not suitable for patients to participate in this study. Note: Patients with any of these conditions cannot be included in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Repeatable Battery for the Assessment of Neuropsychological Status; | — |
Secondary
| Measure | Time frame |
|---|---|
| CRP;Neurofilament Lightchain NfL;IL-6;brain-derived neurotrophic factor;TNF-a;PSQI;HAMD;Moca;Neuron-Specific EnolaseNSE;HAMA;s100ß;Glial Fibrillary Acidic Protein; | — |
Countries
china
Contacts
Public Contactyulan Ren
Chengdu University of Tranditonal Chinese Medicine
Outcome results
None listed