Pancreaticoduodenectomy in elderly patients
Conditions
Interventions
Control Group:On the basis of routine postoperative treatment, 500 ml of 5% glucose sodium chloride is infused through a nasointestinal tube at 12 hours postoperatively, and the nutrient solution prep
Observation Group:On the basis of the control group, rhubarb nasal feeding is administered through a nasointestinal tube at 6 hours postoperatively (30g of raw rhubarb powder is brewed with 100mL of w
Sponsors
Jining Medical University Affiliated Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: Aged from 60~80 years old; With a clear preoperative diagnosis; With malnutrition and in need of enteral nutrition support; The patient voluntarily accepts the treatment plan of this study and signs the informed consent form.
Exclusion criteria
Exclusion criteria: Abnormal cardio-pulmonary-renal function and coagulation indexes and intolerance to gastrointestinal function; Allergic to Rheum officinale or components of enteral/parenteral nutrition solutions; Voluntarily refuse to accept the treatment plan of this study; Meeting the inclusion criteria but failing to implement enteral nutrition as planned after inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stress Indicators 72 hours after Surgery (Cortisol [COR] Adrenocorticotropic Hormone [ACTH] Epinephrine [EPI]);Inflammatory Indicators 72 hours after Surgery (C-reactive Protein [CRP] Interleukin-6 [IL-6]);Time of First Defecation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life;Occurrence of Adverse Events;Patient Comfort and Satisfaction; | — |
Countries
China
Contacts
Public Contactzhangpeilu
Jining Medical University Affiliated Hospital
Outcome results
None listed