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Effect of thunderbolt moxibustion based on "reinforcing Qi and activating blood" on chemotherapy-induced peripheral neurotoxicity in patients with colorectal cancer and moxibustion time-moxibustion effect study

Effect of thunderbolt moxibustion based on "reinforcing Qi and activating blood" on chemotherapy-induced peripheral neurotoxicity in patients with colorectal cancer and moxibustion time-moxibustion effect study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001054
Enrollment
Unknown
Registered
2025-05-27
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Thunderbolt moxibustion group A:On the basis of the control group, thunderbolt moxibustion treatment was given, followed by moxibustion bilateral Laogong and Yongquan, with point, press, kneading and
Thunderbolt moxibustion group C:Thunderbolt moxibustion was given on the basis of the control group. The operation method, acupoint selection and course of treatment were the same as those of thunderb
Thunderbolt moxibustion group B:Thunderbolt moxibustion was given on the basis of the control group. Operation method, acupoint selection and course of treatment were the same as thunderbolt moxibusti
Control group:Routine nursing and health education were used. Routine care includes daily life emotional care dietary guidance and other contents. Health education includes keeping warm wearing cotton

Sponsors

Affiliated Hospital of Nanjing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Pathologically confirmed diagnosis of colorectal cancer; (2) 18 to 75 years of age; (3) the first use of XELOX chemotherapy; (4) at least 1 month before the trial did not use calcium channel blockers, tricyclic antidepressants, membrane stabilization drugs; (5) patients voluntarily joined the study and signed informed consent.

Exclusion criteria

Exclusion criteria: (1) suffering from other diseases that can easily cause peripheral neuropathy, such as diabetes, Parkinson 's disease; (2) having serious cardiovascular and cerebrovascular diseases or abnormal liver and kidney function; (3) bone marrow suppression and coagulation dysfunction; (4) suffering from mental or psychological diseases, can not cooperate with the treatment; (5) moxibustion site skin ulceration; (6) excessive heat syndrome or yin deficiency and fire excess and other moxibustion contraindications; (7) thunderbolt moxibustion smoke or drug allergy.

Design outcomes

Primary

MeasureTime frame
chemotherapy-induced peripheral neuropathy assessment tool, CIPNAT;

Secondary

MeasureTime frame
EORTC QLQ-C30;Numerical Rating Scale, NRS;Berg Balance Scale, BBS;Thermal radiation value of infrared thermal imaging;

Countries

CHINA

Contacts

Public ContactHe Yanyan

Affiliated Hospital of Nanjing University of Chinese Medicine

hyy70345@126.com13770716915

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026