perioperative pain
Conditions
Interventions
OFA group:Local anesthesia+electical acupuncture acupoint stimulation
Sufentanil group:Local anesthesia+Sufentanil
Sponsors
Xiangyang Central Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1: Age between 60-80 years old;Inclusion criteria: 2: ASA status I -? 3:undergoing percutaneous kyphoplasty under local anesthesia
Exclusion criteria
Exclusion criteria: 1: individuals with a history of neurological and psychiatric disorders such as schizophrenia depression etc. who areunable to communicate 2:ndividuals with opioid dependence and frequent use of painkillers. 3:Previous history of cerebral infarction and cerebral hemorrhage 4: History of myocardial infarction or severe coronary heart disease (stenosis degree>80%) that cannot tolerate Pkpsurgery uncontrolled hypertension; Patients with implanted pacemakers; 5:Pathological spinal compression fractures (such as bone tumors etc.) 6: Patients who feel dizzy or cannot tolerate acupuncture 7:Participated in other clinical studies within the past 3 months of enrollment. 8: refuse to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative fatigue;weighted NRS at 6, 24, 48 hours after surgery, and on postoperative day 30;intraopeative average NRS score;15-item quality of recovery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The levels ofthe expression levels of inflammatory factors IL-10 within 24 hours after surgery;The contents of leukocytes lymphocytes and neutrophils in peripheral blood;The levels of a7nAChR receptors within 24 hours after surgery;The levels ofthe expression levels of inflammatory factors TNF-a within 24 hours after surgery;The levels of the expression levels of inflammatory factors IL-1ß within 24 hours after surgery;Intraoperative sufentanil dosage; | — |
Countries
China
Contacts
Public ContactXingrui Gong
Xiangyang Central Hospital
Outcome results
None listed