FindTrial
Sign In

Clinical study on the intervention of mild cognitive impairment in vascular Parkinson's syndrome with the acupuncture method of "Tiao ShenYi Zhi"

Clinical study on the intervention of mild cognitive impairment in vascular Parkinson's syndrome with the acupuncture method of "Tiao Shen Yi Zhi"

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001041
Enrollment
Unknown
Registered
2025-05-26
Start date
2025-05-30
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vascular Parkinson's syndrome with mild cognitive impairment

Interventions

Sham acupuncture group:Sham acupuncture
Acupuncture group:"Tiao Shen Yi Zhi" acupuncture therapy
Healthy Control Group:None
Waitlist Control Group:None

Sponsors

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: VaP-MCI patients: (1) Aged 40-80 years and regardless of gender; (2) Meets VaP diagnostic criteria; (3) 20 points<MMSE score = 24 points; (4) 20 points<MoCA scale = 26 points; (5) Right-handed hand; (6) Voluntarily participate in this study and sign the informed consent form. Healthy participants: (1) Aged 40-80 years and regardless of gender; (2) Can provide a 6-month health examination report; (3) Right-handed hand; (4) Voluntarily participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: VaP-MCI patients: (1) Cognitive impairment present before the diagnosis of VaP; (2) Comorbid central nervous system diseases; (3) History of brain surgery; (4) Suicidal tendencies severe schizophrenia or history of antipsychotic medication use; (5) Severe organic diseases or other conditions affecting cognitive function assessment; (6) Contraindications to MRI scanning or inability to cooperate with the examination due to other reasons; (7) Past or current use of medications affecting cognitive function. Healthy participants: (1) History of brain surgery; (2) Comorbid central nervous system diseases; (3) Suicidal tendencies severe schizophrenia or history of antipsychotic medication use; (4) Past or current use of medications affecting cognitive function; (5) Contraindications to MRI scanning or inability to cooperate with the examination due to other reasons.

Design outcomes

Primary

MeasureTime frame
Montreal cognitive assessment (MoCA);—

Secondary

MeasureTime frame
Activity of Daily Living Scale (ADL);Unified Parkinson's disease rating scale-? (UPDRS-?);Transcranial Color Doppler Ultrasonography (TCCD);Mini mental state examination (MMSE);Diffusion Tensor Imaging;Neurofilament light chain protein in serum;—

Countries

China

Contacts

Public ContactPeng Zhang

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

zhangpengc13@163.com13323351918

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026