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Biomarker Research and Effect Evaluation of "Zhi San Zhen" Intervention on Cognitive Function in Community-Dwelling Older Adults with Mild Cognitive Impairment.

Biomarker Research and Effect Evaluation of "Zhi San Zhen" Intervention on Cognitive Function in Community-Dwelling Older Adults with Mild Cognitive Impairment.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001035
Enrollment
Unknown
Registered
2025-05-26
Start date
2025-04-15
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild Cognitive Impairment

Interventions

Sham Acupuncture Group:Sham Acupuncture Combined with CCRT
Blank Control Group:Take no intervention.
Acupuncture Group:Acupuncture Combined with Conventional Care and Rehabilitation Therapy (CCRT)

Sponsors

Zhongshan Third People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1: Aged 60 years and above;2: Diagnosed with mild cognitive impairment;3: No known major cerebrovascular disease dementia or other pathological cognitive impairments;4: No acute functional psychiatric disorders (including schizophrenia or bipolar disorder;5: Volunteers who willingly participate and have signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1: Patients with congenital intellectual disabilities a family history of dementia or those diagnosed with dementia mental illness or other medical or psychological conditions that may cause brain dysfunction. 2: Patients with severe physical illnesses such as severe heart disease kidney failure or other chronic diseases that may affect cognitive function. 3: Patients with a history of alcohol abuse drug addiction long-term use of glucocorticoids antipsychotic drugs sedative-hypnotic drugs or other medications that may affect cognitive function. 4: Patients with other neurological system diseases such as Parkinson's disease stroke and other neurological disorders. 5: Patients with communication or language barriers that affect cognitive function assessment such as severe speech vision or hearing impairments. 6: Patients with allergies to needles or alcohol. 7: Patients who are positive for syphilis or HIV.

Design outcomes

Primary

MeasureTime frame
Montreal Cognitive Assessment;

Secondary

MeasureTime frame
Clinical Dementia Rating;Activities of Daily Living;Magnetic Resonance Imaging (MRI);Pittsburgh Sleep Quality Index;Patient Health Questionnaire-9;

Countries

China

Contacts

Public ContactXinxia Liu

Zhongshan Third People's Hospital

syliuxinxia@163.com13925362628

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026