hand-foot skin reaction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) patients with pathologically confirmed malignancies including liver cancer kidney cancer breast cancer lung cancer etc.; 2) Grade 1 or higher HFSR after receiving polykinase inhibitor targeted drug treatment including sorafinil shunitinib etc.; 3) Age 18 to 80 years; 4) U.S. Eastern Tumor Collaboration Group score (ECOG score): 0 to 2 points; 5) Expected survival = 3 months; 6) No serious organ dysfunction heart liver kidney etc. tests are basically normal; 7) Able to communicate normally and sign informed consent.
Exclusion criteria
Exclusion criteria: 1) the presence of other skin lesions in the hands and feet (such as peripheral neuropathy caused by diabetes or chemotherapy hand and foot syndrome fungal infection of the hands and feet skin trauma inflammation etc.); Use in combination with other drugs that may affect HFSR.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Treatment Efficiency; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain Relief Rate;Targeted treatment completion rate;HF-QOL; | — |
Countries
China
Contacts
China-japan Friendship Hospital