perimenopausal insomnia
Conditions
Interventions
acupuncture group:acupuncture treatment
sham acpuncture group:sham acpuncture treatment
Sponsors
Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Female aged between 40 and 60 years right-handed; (2) Meeting the diagnostic criteria for chronic insomnia based on STRAW+10 and the International Classification of Sleep Disorders Third Edition (ICSD-3); (3) Pittsburgh Sleep Quality Index (PSQI) score > 7; (4) No use of any medications for at least two weeks prior to enrollment; (5) Willing to participate in the study and having signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Individuals with bilateral oophorectomy organic ovarian lesions premature ovarian insufficiency polycystic ovary syndrome or hypothalamic amenorrhea; (2) Individuals with systemic diseases such as hypertension diabetes coronary heart disease or obesity (BMI = 28); (3) Individuals with severe and life-threatening primary diseases involving the cardiovascular cerebrovascular hepatic renal or hematopoietic systems; (4) Individuals with impaired consciousness who are unable to express subjective discomfort; (5) Individuals with a personal or first-degree family history of psychiatric disorders or with organic neurological diseases; (6) Individuals with insomnia caused by alcohol abuse and/or psychoactive substance abuse or dependence (including sleeping pills); (7) Individuals with severe symptoms of depression or anxiety; (8) Individuals with severe headache migraine or a history of head trauma or brain surgery; (9) Individuals who received estrogen selective serotonin reuptake inhibitors (SSRIs) or other replacement therapies within 4 weeks prior to enrollment; (10) Individuals who are pregnant planning to become pregnant or breastfeeding; (11) Individuals with contraindications to MRI such as claustrophobia or implanted metal devices (including metal dental braces).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Insomnia assessment scales; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mood Assessment scales;blood test;Neuroimaging assessment indicators;Neuropsychological assessment scales;Menopause Rating Scale;Gut-related test; | — |
Countries
China
Contacts
Public ContactLili Yang
Chengdu University of Traditional Chinese Medicine
Outcome results
None listed