Coronary Heart Disease
Conditions
Interventions
Qijin Dan group:Qijin Dan and standard Western treatment
Sponsors
Wuxi Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1Patients with a confirmed history of myocardial infarction (MI) or coronary angiography/spiral CT-confirmed coronary stenosis =50% and TCM syndrome differentiation consistent with phlegm-stasis obstruction syndrome or qi deficiency with blood stasis syndrome. 2.Stable vital signs and in good general condition. 3.Age =18 years old. 4.Participants must provide informed consent and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients diagnosed with severe cardiac conditions (e.g. malignant arrhythmias structural heart disease) or acute comorbidities such as cerebral infarction (acute phase) or severe respiratory insufficiency. 2.Patients with severe systemic diseases including: Heart failure (severe) Hepatic dysfunction (AST/ALT >1.5× upper limit of normal) Renal impairment (BUN/Cr above upper limit of normal) Hematologic endocrine or severe primary disorders Malignancy gastrointestinal bleeding peptic ulcers or bleeding tendency (if deemed likely to interfere with trial completion). 3Patients with psychiatric disorders cognitive impairment or legal disability. 4.Pregnant/lactating women women planning pregnancy or hypersensitivity to trial drug components. 5.Participation in another clinical trial within the past 3 months or current enrollment. 6.Unwillingness to comply with study procedures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Matrix Metalloproteinase-2;Insulin-like Growth Factor-1;Hypoxia Inducible Factor 1-alpha; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM syndrome scores;SAQ scores;coronary Gensini scores; | — |
Countries
China
Contacts
Public ContactZhou Yingqi
Wuxi Hospital of Traditional Chinese Medicine
Outcome results
None listed