Postoperative Cognitive Dysfunction (POCD) following Endoscopic Retrograde Cholangiopancreatography (ERCP)
Conditions
Interventions
Intervention group:TEAS Treatment
-Control Group:sham TEAS treatment(non-acupoint electrode placement with no electrical stimulation delivered)
Sponsors
Xinxiang Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18–65 years with a BMI of 18.5–27.9 kg/m² and eligible for ERCP (endoscopic retrograde cholangiopancreatography); (2) American Society of Anesthesiologists (ASA) Physical Status Class I to III; (3) No history of drug allergies or contraindications to related medications.
Exclusion criteria
Exclusion criteria: (1) Preoperative cognitive impairment or abnormal scores on the Mini-Mental State Examination (MMSE <24) or Montreal Cognitive Assessment (MoCA <26); (2) Significant impairment of cardiac pulmonary hepatic or renal function; (3) History of traumatic brain injury neurological disorders or alcohol abuse; (4) Inability to communicate effectively with healthcare providers or cooperate in completing cognitive function assessments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative cognitive dysfunction (POCD); | — |
Secondary
| Measure | Time frame |
|---|---|
| neurofilament light chain protein (NfL); BDNF;S100ß protein; | — |
Countries
China
Contacts
Public ContactZhaolifang
Xinxiang Central Hospital
Outcome results
None listed