Esophageal squamous cell carcinoma
Conditions
Interventions
Patient control group:It is treated according to the current clinical routine method and no drug intervention is done.
Healthy control group:no
Patient treatment group:Jian Pi Jie Du Granules 6g/pack (2 times a day 1 pack each time oral) 21 days of continuous medication for 1 course of treatment
Sponsors
Cancer Hospital of Nantong University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients with pathological or cytological diagnosis of stage II. or III. primary esophageal squamous cell carcinoma and have undergone the first postoperative chemotherapy. 2. Comply with the clinical syndrome differentiation standards of traditional Chinese medicine. 3. Age = 18 years old and = 85 years old good compliance. 4. The patient underwent TP (paclitaxel + cisplatin) chemotherapy regimen and the protocol description: paclitaxel (PTX) 210mg/m2 intravenous infusion d1 + cisplatin (DDP) 30mg/m2/d intravenous infusion d1-3 (21 days for 1 cycle). 5. The patient developed spleen deficiency syndrome after standard TP chemotherapy regimen. 6. The subject has no dysfunction of major organs and has normal blood routine liver kidney and heart functions. 7. Patients who have signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with abnormal thyroid function diabetes or hypertension. 2. Abnormal liver function (alanine aminotransferase aspartate aminotransferase total/direct/indirect bilirubin bile acids etc.) and/or abnormal renal function (urea creatinine uric acid etc.). 3. Mentally ill people. 4. Pregnant or lactating women. 5. History of other tumors within 5 years. 6. Have a family history of genetic disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life; | — |
Secondary
| Measure | Time frame |
|---|---|
| Metabonomics test;Routine blood test;TCM syndrome;Vital signs;Fecal routine;Blood biochemistry;electrocardiogram;Urinalysis; | — |
Countries
China
Contacts
Public ContactGuo-Hua Wei
Cancer Hospital of Nantong University
Outcome results
None listed