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Clinical efficacy and safety evaluation of dissolving acupoint microneedles with tanshinone IIA in the treatment of chronic stable angina

Clinical efficacy and safety evaluation of dissolving acupoint microneedles with tanshinone IIA in the treatment of chronic stable angina

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000991
Enrollment
Unknown
Registered
2025-05-15
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic stable angina

Interventions

Control group 2:The non-DAMNs intervention was applied to the selected acupoints with the selection and procedure identical to those in the treatment group.
Control group 1:According to the previous literature, 7 non meridian and non acupoint points were selected for TSA damns intervention (7 tablets each time), and the operation was the same as that of t
Treatment group:Neiguan (PC6, bilateral), Danzhong (RN17), Xinshu (BL15, bilateral), and Zusanli (ST36, bilateral) were used for administration, and TSA-DAMNs were clamped with sterile forceps for rap
Four weeks is a course of treatment, a total of two courses, 24 treatments.
Control group 3:Conventional Western medicine treatment was administered without any additional interventions.

Sponsors

the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of ACC/AHA coronary heart disease stable angina pectoris (CCS grade I.-IV. can be included) 2. 35 years old< = age< = 80 years old both men and women; 3. Have not taken psychotropic drugs in the past 3 months; 4. No serious breakage rash etc. no history of adhesive tape allergy in the treatment of local skin; 5. Those who have a certain level of knowledge and culture (because it is necessary to complete the angina diary and fill in the relevant questionnaires) have good compliance are willing to cooperate with the research and sign the informed consent form; Note: Only patients who meet the above 5 criteria can be included in this study.

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating women and those who have childbearing requirements in the past six months; 2. Patients with hematopoietic system diseases heart liver spleen lung kidney and other serious primary diseases and high-sensitivity constitution; 3. Patients with acute coronary syndrome (including acute myocardial infarction unstable angina) severe arrhythmia atrial fibrillation primary cardiomyopathy valvular heart disease; 4. Those who have received acupuncture treatment for cardiovascular disease in the past 3 months and are participating in other clinical trials. Note: Subjects who meet any of the above criteria are not allowed to be included.

Design outcomes

Primary

MeasureTime frame
Anginal Frequency;

Secondary

MeasureTime frame
24-hour dynamic electrocardiogram ST-T segment change results;Score of VAS scale;Score of Seattle Angina Questionnaire;

Countries

China

Contacts

Public ContactCui Jin;Xue Kaiyang;Zhang Zhihui

the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine

516260179@qq.com+86 139 8502 6278

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026