Post-Stroke Cognitive Impairment
Conditions
Interventions
Sham electroacupuncture group:On the basis of ordinary acupuncture, non output current electroacupuncture instrument is used for treatment
Electroacupuncture group:Treatment with electro-acupuncture device on the basis of ordinary needling
Sponsors
The Third Affiliated Hospital of Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Western diagnostic criteria were met according to the Western diagnostic criteria for vascular cognitive impairment in the Chinese Guidelines for the Diagnosis and Treatment of Vascular Cognitive Impairment (2024 edition) developed by the Vascular Cognitive Impairment Branch of the Chinese Stroke Association.1) Cognitive-related complaints were present and neuropsychological measurements showed impairment in one or more cognitive domains. 2) Evidence of vascular cerebral injury was present including vascular risk factors history of stroke neurological syndromes of cerebrovascular injury and imaging evidence of cerebrovascular injury Evidence of vascular brain injury: vascular risk factors history of stroke neurologic syndromes of cerebrovascular injury and imaging evidence of cerebrovascular injury but not necessarily all of the above; 3) predominance of vascular brain injury in cognitive impairment: the predominance of vascular brain injury in cognitive impairment should be clear especially when combined with the pathology of dementia and the clinical features need to be the following: sudden onset of the disease the onset of cognitive impairment temporally associated with one or more stroke events (2) meet the Chinese medicine diagnostic criteria for vascular cognitive impairment in the Guidelines for Chinese Medicine Treatment of Mild Cognitive Impairment of Vascular Origin (2024); (3) have a Mini-Mental State Examination (MMSE) score of 12-24; Montreal Cognitive Assessment Scale (MCS) score of 12-24; and (4) have a clinical diagnosis of vascular cognitive impairment of vascular origin. (4) The score of Montreal Cognitive Assessment (MoCA) is <24; cognitive impairment exists but does not reach the level of severe dementia; the score of National Institutes of Health Stroke Scale (NIH Stroke Scale) is =8; the score of Ascertain Dementia-8 (AD-8) is =8; the score of Very Early Dementia Screen (AD-8) is <3; and (5) the score of Montreal Cognitive Assessment (MCA) is <4. Dementia 8 AD-8) score <2; (4) age between 35-80 years; (statistical analysis written to stratify by age) (5) basic communication skills with Mandarin as the primary language (communication language is sufficient) and at least one stable caregiver; (6) signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Combined heart liver kidney and other organs as well as the endocrine system and hematopoietic system and other serious primary chronic diseases serious cardiovascular and cerebrovascular diseases; (2) Localized body surface prone to herpes ulcers and other skin diseases or keloidal scarring which is unsuitable for acupuncture treatment; (3) Unsuitable for repetitive MRI examination such as claustrophobia aneurysm embolization after the operation etc.; (4) Prior to the current onset of the disease has cognitive impairment or other serious neurological or psychiatric disorders with unstable control; (5) other patients determined by the clinical laboratory staff to be unsuitable for this study; (6) those who have participated in clinical research on related diseases in the last 3 months;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neuropsychological Test Battery;Clinical Dementia Rating;Montreal Cognitive Assessment;Mini-Mental State Examination; | — |
Secondary
| Measure | Time frame |
|---|---|
| Stroke-Specific Quality of Life Scale;Chinese Medicine Score Assessment;Modified Barthel Index;Hamilton Depression Scale;electroencephalogram;Near-infrared spectroscopy;Modified Rankin Scale;Pittsburgh sleep quality index;Magnetic Resonance Imaging; | — |
Countries
China
Contacts
Public ContactRuijie Ma
The Third Affiliated Hospital of Zhejiang Chinese Medical University
Outcome results
None listed