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A cohort study on the synergistic diagnosis and treatment model of chronic liver failure and its diagnosis and treatment protocol by combining Chinese and Western medicine with the "state-target pattern identification"

A cohort study on the synergistic diagnosis and treatment model of chronic liver failure and its diagnosis and treatment protocol by combining Chinese and Western medicine with the "state-target pattern identification"

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025000983
Enrollment
Unknown
Registered
2025-05-14
Start date
2023-08-09
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic liver failure

Interventions

Treatment group:Basic Western Medicine+state-target pattern identification

Sponsors

Shanghai University of Traditional Chinese Medicine Affiliated City Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1)Meets the diagnostic criteria for CLF. 2) Age 18-75 years old. 3)Gender is not limited. 4)Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1)Acute liver failure subacute liver failure. 2)CLF not caused by HBV infection. 3)Pregnant or breastfeeding women. 4)Primary liver cancer 5) Combination of other serious systemic diseases such as malignant tumour etc. suffering from mental illness. 6)Human immunodeficiency virus (HIV) positive; 7) Participated in other clinical trials within the past 3 months. 8)The enrolment has been combined with cerebral oedema serious infection type I hepatorenal syndrome and gastrointestinal haemorrhage and so on.

Design outcomes

Primary

MeasureTime frame
liver transplantation rate;Mortality ;

Secondary

MeasureTime frame
Single hospitalisation costs;Length of single hospitalisation;Quality of Life Scale;CTP;Frequency of hospitalisation;MELD;coagulation;biochemistry;Symptom score;

Countries

China

Contacts

Public ContactHongming Nie

Shanghai University of Traditional Chinese Medicine Affiliated City Hospital of Traditional Chinese Medicine

Beining0630@126.com+86 137 9543 3078

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026