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Multi-Omics Analysis of the Biological Basis of Phlegm-Dampness Syndrome in Coronary Heart Disease

Multi-Omics Analysis of the Biological Basis of Phlegm-Dampness Syndrome in Coronary Heart Disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025000979
Enrollment
Unknown
Registered
2025-05-13
Start date
2025-06-06
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary heart disease

Interventions

Coronary heart disease with non-phlegm-dampness syndrome:None
Healthy control:None
Coronary heart disease with phlegm-dampness syndrome:None

Sponsors

the First Affiliated Hospital of Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: (1) Age = 18 years with no restriction on gender (2)Willing to voluntarily participate in this study, having signed the informed consent, and ready to cooperate with the investigation procedures (3)Patient inclusion criteria: Meeting the diagnostic criteria for coronary heart disease. In order to avoid biological errors caused by different stages of the disease, the inclusion criteria were further defined as unstable angina (4)Health control group inclusion criteria: Not meeting the diagnostic criteria for coronary heart disease, without clinical evidence of myocardial ischemia

Exclusion criteria

Exclusion criteria: (1)Severe hepatic and renal dysfunction (2)Malignant tumors (3)Complicated by severe cardiac conditions, such as severe valvular stenosis or insufficiency, viral myocarditis, acute myocardial infarction, etc (4)Acute and critical illness requiring immediate treatment, such as acute phase of cerebral infarction, acute upper gastrointestinal bleeding, diabetic ketoacidosis, etc (5)Surgery or acute infection within the last 2 weeks (6)Other conditions deemed by the researcher as unsuitable for inclusion, including but not limited to pregnancy, fever, etc

Design outcomes

Primary

MeasureTime frame
Traditional Chinese Medicine syndrome;Metabolomics;Proteomics;

Secondary

MeasureTime frame
Biochemistry;Lipid profile;Glycosylated hemoglobin;Blood routine;Liver function tests;Severity of coronary artery disease;Cardiovascular disease risk factors;Cardiac enzyme;

Countries

China

Contacts

Public ContactZHONG Sen-jie

the First Affiliated Hospital of Guangzhou University of Chinese Medicine

634960445@qq.com15274970800

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026