Hypertension
Conditions
Interventions
Western Standard Treatment Group:Western Standard Treatment
GroupXiangya Dan plus Standard Treatment Group:Treatment with Xiangya Dan on the basis of Western Standard Treatment
Huoxiangdan plus Standard Treatment Group:Treatment with Huoxiangdan on the basis of Western Standard Treatment
Huolongdan plus Standard Treatment Group:Treatment with Huolongdan on the basis of Western Standard Treatment
Sponsors
Wuxi Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Aged between 18 and 80 years old regardless of gender 2.Have not taken antihypertensive drugs in the past 2 weeks or have been taking antihypertensive drugs for more than 2 weeks 3.Obese with a firm abdomen: Obesity and leanness are classified according to the standard weight (standard weight = height (cm) - 105 unit: Kg). Those who exceed the standard weight are considered obese. In addition for the judgment of a soft and firm abdomen if there is any dispute it should be classified as Yangming type according to the qi transformation sequence of traditional Chinese medicine seasonal theory 4.The average of three consecutive readings of systolic blood pressure during the screening visit is within the range of 140-159 mmHg and/or diastolic blood pressure is 90-99 mmHg and the risk stratification assessment is low risk 5. The average 24-hour ambulatory systolic blood pressure is =130 mmHg 6.Agree to participate in the trial and can adhere to follow-ups visiting the hospital by themselves 7.Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Suspected or confirmed secondary hypertension 2.Ambulatory blood pressure monitoring is unqualified (valid readings <70% 3.<20 readings during the daytime waking period 4.<7 readings during the nighttime sleeping period) 5.Medications that must be used for other diseases may affect blood pressure such as a-receptor blockers used by males for benign prostatic hyperplasia 6.Occurrence of cerebrovascular diseases such as stroke myocardial infarction or heart failure within the past 6 months 7.History of atrial fibrillation or frequent arrhythmias 8.Liver function test results (ALT AST TBL = 2 times the upper limit of normal or serum creatinine = 176 umol/L or serum potassium = 5.5 mmol/L) 9.Pregnant or breastfeeding women 10. Concurrent other diseases that make participation in the trial unsuitable such as thyroid diseases that are currently being medicated acute infectious diseases chronic mental illnesses tumors etc. 11.Poor compliance with the research process.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure control status (effectiveness rate intensive target achievement rate).;Blood pressure;Serum concentration levels of biochemical markers (GPT/GOT/AKP/gamma-GT) before and after treatment.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight.;Serum electrolytes (potassium sodium chloride) blood biochemistry (creatinine uric acid liver and kidney function blood glucose) and blood lipids (total cholesterol triglycerides high-density lipoprotein cholesterol low-density lipoprotein cholesterol).;Traditional Chinese Medicine Syndrome Points;Eectrocardiogram; | — |
Countries
China
Contacts
Public ContactWang Yuan
Wuxi Traditional Chinese Medicine Hospital
Outcome results
None listed