Pre-type 2 diabetes
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Fasting blood glucose (FPG) 6.1-6.9 mmol/L or 2 hours postprandial blood glucose (2h-PBG) 7.8-11.0 mmol/L or HBA1c 5.7-6.4%; Age 18-65 years (inclusive); Body mass index (BMI) between 19-35 kg/m²; Try to keep diet exercise medication and other habits stable during the experiment. Voluntarily sign informed consent and be able to cooperate with the follow-up within the study cycle.
Exclusion criteria
Exclusion criteria: Weight stable Weight gain or weight loss < 5kg in the past 3 months; Serious organic or metabolic diseases (including serious liver and kidney diseases such as malignant tumors cirrhosis or kidney failure); Severe cardiovascular and cerebrovascular diseases (heart failure myocardial infarction cerebral hemorrhage stroke etc. within half a year); Infectious diseases; Mental illness; Heavy drinking (=3 drinks per day =21 drinks per week); Medications that may affect the intestinal flora (such as antibiotics medications for intestinal diseases etc.) were taken 1 month before enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FBG(fasting blood-glucose); | — |
Secondary
| Measure | Time frame |
|---|---|
| Height;High density lipoprotein cholesterol;Weight;Vascular hardness;Blood glucose 2 hours after meal;Glycated hemoglobin;Total cholesterol;Serum non-targeted metabolomics;Blood Pressure;Liver function;Hip circumference;Intestinal flora;Kidney function;Urine routine;Visceral fat;Waist circumference;Low density lipoprotein cholesterol;Body fat content;TG (Triglyceride ); | — |
Countries
China
Contacts
Qiqihar Medical University