unstable angina
Conditions
Interventions
test team:On the basis of conventional western medicine treatment Guanxin Danshen capsule ( oral administration 3 capsules each time 3 times a day ) and Chuanxinlian tablet ( oral administration 2 tab
control group:conventional western medicine treatment
Sponsors
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1 : Conform to the diagnostic criteria of unstable angina pectoris of coronary heart disease 2 : Aged 18-80 years 3 : TCM syndrome differentiation belongs to blood stasis syndrome ( including qi stagnation and blood stasis qi deficiency and blood stasis and other complex syndromes ). 4 : Those who follow the doctor 's advice and have good medication compliance voluntary follow-up and signed informed consent
Exclusion criteria
Exclusion criteria: 1: Complicated with severe valvular heart disease severe arrhythmia 2: Patients with cardiac function = grade III or EF 2.5 mg / dl in men and > 2.0 mg / dl in women 6: Liver dysfunction basic liver enzyme detection > 3 times the normal value 7: Complicated with nervous system diseases malignant tumors hematopoietic system and other serious primary diseases organ transplant patients 8: Those who also participated in other clinical trials or took other Chinese patent medicines during treatment. 9: Lactating or pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Traditional Chinese Medicine symptom score; Angina score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood stasis syndrome score; P-selectin;ET-1;vWF;TNF-a;platelet aggregation rate;IL-1ß;MCP-1;miR-34a-5p;ICAM-1; | — |
Countries
China
Contacts
Public ContactMa Xiaojuan
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Outcome results
None listed