Knee Osteoarthritis
Conditions
Interventions
Treatment group:Tuina Therapy
Control group:Diclofenac Sodium Transdermal Patch
Sponsors
Shanghai Municipal Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Meeting the above diagnostic criteria for knee osteoarthritis or having been clinically diagnosed with KOA; 2) Meeting the Kellgren-Lawrence (K-L) classification of grade I-III on standing knee X-ray films: Grade I: Suspected narrowing of the knee joint space with possible minor osteophytes (bony protrusions at the edge of the knee joint); Grade II: Clear presence of small osteophytes with suspected narrowing of the joint space; Grade III: Presence of moderate osteophytes with clear narrowing of the joint space and sclerotic changes; 3) Numerical Rating Scale (NRS) score of 3 or above (on a scale of 0-10); 4) Age between 40 and 80 years old with no gender restrictions; 5) Voluntary participation in this trial and signing the informed consent form.
Exclusion criteria
Exclusion criteria: 1) History of knee trauma and surgery; 2) Other knee treatment history in the past 6 months; 3) Knee joint diseases such as tumors tuberculosis osteomyelitis etc.; 4) Severe liver and kidney dysfunction severe cardiovascular disease diabetes mental illness; 5) Rheumatoid arthritis fibromyalgia or other systemic rheumatic immune diseases; 6) Total knee replacement or other major lower extremity surgeries in the past 6 months or planned within the next 9 months; 7) Severe hearing or vision impairment; 8) History of allergy to non-steroidal anti-inflammatory drugs; 9) Alcohol abuse and drug abuse; 10) Currently participating in another clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The changes in WOMAC pain scale values after 4 weeks of treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| MyotonPRO;Timed Up and Go test;Short Physical Performance Battery;Short Form-36 Health Survey;the Western Ontario and McMaster Universities Osteoarthritis Index; | — |
Countries
China
Contacts
Public ContactYAO Fei
Shanghai Municipal Hospital of Traditional Chinese Medicine
Outcome results
None listed