dilated cardiomyopathy
Conditions
Interventions
experimental group:Conventional Western Medicine+placebo
experimental group:Conventional Western Medicine+Qishen Yangxin granules
Sponsors
Guanganmen Hospital China Academy of Chinese Medical Sciences Beijing China
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) aged 18-75 years old, (2) meeting the diagnostic criteria of DCM in the 2018 Chinese Guidelines for the Diagnosis and Treatment of Dilated Cardiomyopathy, (3) Chinese medicine diagnosis of cardiac yang insufficiency, (4) NYHA Cardiac Function Class II-IV, (5) voluntarily signing an informed consent form, and (6) not taking any other Chinese herbal medicines in the last 2 weeks.
Exclusion criteria
Exclusion criteria: (1) Comorbidities of severe hepatic or renal abnormalities, hematologic disorders, respiratory failure, and malignancy, (2) Pregnant or lactating women, (3) Cognitive or communication disorders, (4) Allergies, and (5) Participating in other interventional clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left ventricular ejection fraction LVEF (Simpsons method); | — |
Secondary
| Measure | Time frame |
|---|---|
| Left Atrial Diameter (LAD);Interventricular septal thickness (IVS);MACCE;Minnesota Heart Failure Quality of Life Scale (MLHFQ);Left ventricular end-diastolic internal diameter (LVEDD);NYHA Cardiac Function Classification;NT-proBNP;Left ventricular post-diastolic wall thickness (LVPWd);CK-MB;Chinese Medicine Score;Left ventricular short-axis shortening (LVFS);TNI; | — |
Countries
China
Contacts
Public ContactLi Jun
Guanganmen Hospital China Academy of Chinese Medical Sciences Beijing China
Outcome results
None listed