Mild Cognitive Impairment
Conditions
Interventions
Control Group:Placebo + Cognitive Training
Experimental Group:Anoectochilus roxburghii Concentrate + Cognitive Training
Sponsors
Fujian Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: a. Meet diagnostic criteria for mild cognitive impairment (MCI) and Syndrome of the Traditional Chinese Medicine type of Intense Fire in the Heart and Liver (Xin-Gan Huo Wang Zheng); b. Age = 60 years; c. No gender restrictions; d. Education level: At least primary school education with willingness to participate in the study and ability to cooperate in Montreal Cognitive Assessment (MoCA); e. Voluntary participation with signed informed consent form.
Exclusion criteria
Exclusion criteria: a. Moderate-to-severe cognitive impairment including: Clinically diagnosed dementia (multi-domain cognitive deficits + dependency in daily living activities) MoCA score significantly low (<18) or severe impairment in ADL (Activities of Daily Living) Sensory/language impairments preventing compliance with assessments b. Allergy to the decoction of fresh Anoectochilus roxburghii or its related components; c. Patients with constitution types such as: Yang deficiency Balanced constitution Phlegm-dampness Qi deficiency; d. Currently receiving other treatments that may significantly affect cognitive function such as: Anti-dementia drugs Antipsychotic medications e. Severe vision/hearing impairment aphasia or inability to complete cognitive scale assessments; f. History of drug/alcohol abuse or uncontrolled psychiatric disorders (e.g. depression); g.Currently participating in other clinical trials h.A history of allergies to placebo ingredients (xylitol caramel color) or an inability to accept the possibility of being assigned to the inactive drug group.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment (MoCA); | — |
Secondary
| Measure | Time frame |
|---|---|
| Untargeted Metabolomics; | — |
Countries
China
Contacts
Public ContactWeidong He
Fujian Provincial People's Hospital
Outcome results
None listed