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A multicenter randomized controlled study based on the application of intestinal enema in the treatment of sepsis based on "treating the lungs from the intestines".

A multicenter randomized controlled study based on the application of intestinal enema in the treatment of sepsis based on "treating the lungs from the intestines".

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000917
Enrollment
Unknown
Registered
2025-05-07
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Control group:Basic treatment + warm water retention enema
Experimental group:Basic treatment + intestinal adjustment prescription retains enema

Sponsors

Science of Inner Mongolia Autonomous Region Office of Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria for sepsis; (2) The syndrome differentiation of TCM is in line with the empirical type of stomach heat and intestines; (3) Age 18 years or older gender not Limit. (4) Sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) digestive system surgery of the latter; (2) Gastrointestinal dysfunction caused by primary gastrointestinal diseases; (3) Severe primary diseases that affect survival including: uncontrolled malignant tumors that have metastasized in multiple places and cannot be resected hematological diseases HIV etc.; (4) Those with allergies or those who are known to be allergic to therapeutic drugs; (5) Pregnant and lactating women; (6) Those who suffer from mental illness.

Design outcomes

Primary

MeasureTime frame
Improvement degree of SOFA score;

Secondary

MeasureTime frame
Gastrointestinal function score;Length of stay in ICU;TCM Syndrome Points;ICU case fatality rate;28-day all-cause case fatality rate;Duration of mechanical ventilation;APACHEII;Lung function indicators;

Countries

China

Contacts

Public ContactZhang Ruifen

Health Commission of Inner Mongolia Autonomous Region

15849112400@163.com15849112400

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026