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Treatment of gastroesophageal reflux disease with anxiety and depression in Beijing based on the theory of brain gut homology

Clinical study on the treatment of gastroesophageal reflux disease with anxiety and depression in Xinjiang and Beijing based on brain-intestinal homology theory

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000913
Enrollment
Unknown
Registered
2025-05-07
Start date
2025-05-30
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastroesophageal reflux disease

Interventions

Sponsors

Wangjing Hospital Chinese Academy of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Simultaneously meet the diagnostic criteria for GERD in Western medicine, traditional Chinese medicine syndrome types, and anxiety and depression (2) Gender is not limited, age is between 18-80 years old. (3) Patients who voluntarily participate in this research survey and are able to complete the survey data with high compliance.

Exclusion criteria

Exclusion criteria: (1) Digestive endoscopy revealed gastrointestinal tumors, cirrhosis ascites, gastrointestinal obstruction, and major abdominal surgery History; There are certain related esophageal diseases, such as fungal esophagitis, corrosive esophagitis, and drug-induced esophagitis Diseases such as inflammation. (2) Suffer from 17 diseases that cause esophageal motility disorder, such as scleroderma, diabetes and psychosis Systemic diseases, etc. (3) Patients with mental system disorders who have unclear symptoms or are unable to communicate with doctors normally. (4) Patients aged between 18-80, pregnant women, and breastfeeding women. (5) Suffering from systemic diseases that affect sleep, such as arrhythmia, heart failure, asthma, etc.

Design outcomes

Primary

MeasureTime frame
self-rating depression scale;self-rating anxiety scale;Traditional Chinese Medicine Symptom Rating Scale;Gastroesophageal Reflux Disease self-assessment scale;

Secondary

MeasureTime frame
5-hydroxytryptamine;tumor necrosis factor - a;Interleukin-1ß;

Countries

China

Contacts

Public ContactYiqingZhang

Wangjing Hospital Chinese Academy of Traditional Chinese Medicine

xhww1979@163.com13699183372

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026