chronic urticaria
Conditions
Interventions
Control group:Sham acupuncture with Ebastine
Treatment group:Acupuncture with Ebastine
Sponsors
Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Those who meet the diagnostic criteria for chronic spontaneous urticaria in the EAACI/GA2LEN/EDF/WAO Urticaria Diagnostic Guidelines (2022 edition) and Chinese Urticaria Diagnostic Guidelines (2018 edition); (2) Right-handed; those who are 18 years old = age = 70 years old with = 6 years of education of both sexes; (3) No metallic implants in the body and no contraindication to fMRI scanning; (4) No use of antihistamines within 2 weeks prior to study entry and no use of steroid hormones or immunosuppressive drugs within 1 month; (5) Previously taken antihistamines and insensitive to antihistamines; (6) Those who are not participating in other ongoing clinical studies; (7) Those who have signed the informed consent form and voluntarily participate in this study. Patients who meet the above seven criteria are eligible for inclusion in this study.
Exclusion criteria
Exclusion criteria: (1) People with claustrophobia and other contraindications to nuclear magnetic examination; (2) Those who are unconscious unable to express subjective discomfort symptoms and psychiatric patients; (3) People with progressive malignant tumors or other serious consumptive diseases easily combined with infection and bleeding; (4) People with serious primary diseases such as cardiovascular hepatic renal digestive and hematopoietic systems; (5) Pregnant and lactating women. Note: Patients who meet any 1 of the above criteria will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Self-Rating Anxiety Scale (SAS);Urticaria Control Test (UCT);Pruritus Visual Analogue Scale (VAS);urticaria activity score over 7 days (UAS7);Chronic Urticaria-Quality of Life (CU-Q2oL);Self-Rating Depression Scale (SDS);Pittsburgh sleep quality index (PSQI); | — |
Countries
China
Contacts
Public ContactZou Zihao
Chengdu University of Traditional Chinese Medicine
Outcome results
None listed