GOUT
Conditions
Interventions
Acute phase A group :add TongFengHeJi
Acute phase B group :not add TongFengHeJi
Control group:No intervention
Relief period:No intervention
Sponsors
Jiangsu Integrated Traditional Chinese and Western Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age between 18 and 75 years old (including boundary values) gender not limited; (2) Patients in the acute and remission phases meet the diagnostic criteria for gouty arthritis; (3) Voluntarily participate in the experiment and sign the informed consent form; (4) The control group of healthy individuals had normal blood uric acid levels.
Exclusion criteria
Exclusion criteria: (1) Allergic constitution such as any known research drug (2) Combined with potentially life threatening diseases such as serious cardiovascular diseases brain diseases liver diseases kidney diseases hematological diseases lung diseases or diseases that can directly affect survival such as cancer or AIDS; (3) Merge patients with severe liver and kidney dysfunction (4) Patients with peptic ulcers accompanied by bleeding or perforation; (5) Patients with infectious diseases including tuberculosis hepatitis B etc; (6) Has participated in other ongoing clinical researchers; (7) Those who have planned to have children within 6 months or are pregnant or breastfeeding; (8) Individuals with mental illness and lack of autonomous behavioral ability; (9) Individuals with a history of drug or alcohol abuse; (10) Has the potential to reduce the likelihood of enrollment and other easily lost to follow-up situations; (11) Patients in the remission period have not used uric acid lowering drugs or have been steadily using related drugs for more than 2 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HIF-1a;ESR;ICAM-1;VEGF;Urine PH;ET-1;IL-2\IL-4\IL-6\IL-10\TNF-a\IFN-?;carbon dioxide combining power;Plasma lactate;CRP;NO; | — |
Secondary
| Measure | Time frame |
|---|---|
| the frequency of using Etoricoxib;echocardiography;EPO;Time for improvement of joint pain;uric acid change value;Carotid artery endothelial thickness; | — |
Countries
China
Contacts
Public ContactYang Yaxu
Jiangsu Integrated Traditional Chinese and Western Medicine Hospital
Outcome results
None listed