Stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.1 Inclusion criteria for patients with acute ischaemic stroke 1) The patients also met the western medical diagnostic criteria for ischaemic stroke and all were diagnosed by cranial CT and/or MRI. 1) Acute onset of disease; 2) Focal neurological deficits (weakness or numbness of one side of the face or limbs speech disorders etc.) and in a few cases comprehensive neurological deficits; 3) Symptoms or signs of unlimited duration (when imaging shows a responsible ischaemic lesion) or lasting more than 24h (when imaging of a responsible lesion is lacking); 4) Exclusion of non-vascular causes; 5) Brain CT/MRI to exclude cerebral haemorrhage. 2) Age of onset = 18 years; 3) Onset within 72 hours; 4) Signed an informed consent form agreeing to participate in this study. 1.2 Healthy control group inclusion criteria: 1) Age =18 years old; 2) Signed informed consent to participate in this study; 3) No history of coronary heart disease stroke TIA and other cardiovascular diseases.
Exclusion criteria
Exclusion criteria: 2.1 Exclusion criteria for patients with acute ischaemic stroke: 1) Patients with secondary ischaemic stroke caused by brain tumour traumatic brain injury cerebral parasitosis cerebral amyloid angiopathy arteritis and intracranial vascular malformation; 2) severe heart disease cardiac insufficiency liver dysfunction renal insufficiency respiratory failure malignant tumour gastrointestinal bleeding at the onset; 3) Psychiatric patients; 4)Pregnant and lactating women; 5) Patients with drug and alcohol abuse; Patients who are participating in other clinical trials. 2.2 Healthy control group exclusion criteria: 1) Psychiatric patients; 2) Pregnant and lactating women; (iii) Patients with drug abuse or alcohol abuse; (iv) Patients who are participating in other clinical trials; Patients who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metabolic pathways related to differential metabolites in each group;Differential metabolites of Yin and Yang syndrome of ischemic stroke; | — |
Countries
China
Contacts
Guangdong Hospital of Traditional Chinese Medicine