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To explore the biomarkers of ischemic stroke "Yin and Yang syndrome" differentiation and treatment system based on metabolomics

To explore the biomarkers of ischemic stroke "Yin and Yang syndrome" differentiation and treatment system based on metabolomics

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025000896
Enrollment
Unknown
Registered
2025-05-06
Start date
2025-05-17
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Stroke Yang type syndrome group:N/A
Control group:N/A
Stroke Yin type syndrome group:N/A

Sponsors

Guangdong Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1.1 Inclusion criteria for patients with acute ischaemic stroke 1) The patients also met the western medical diagnostic criteria for ischaemic stroke and all were diagnosed by cranial CT and/or MRI. 1) Acute onset of disease; 2) Focal neurological deficits (weakness or numbness of one side of the face or limbs speech disorders etc.) and in a few cases comprehensive neurological deficits; 3) Symptoms or signs of unlimited duration (when imaging shows a responsible ischaemic lesion) or lasting more than 24h (when imaging of a responsible lesion is lacking); 4) Exclusion of non-vascular causes; 5) Brain CT/MRI to exclude cerebral haemorrhage. 2) Age of onset = 18 years; 3) Onset within 72 hours; 4) Signed an informed consent form agreeing to participate in this study. 1.2 Healthy control group inclusion criteria: 1) Age =18 years old; 2) Signed informed consent to participate in this study; 3) No history of coronary heart disease stroke TIA and other cardiovascular diseases.

Exclusion criteria

Exclusion criteria: 2.1 Exclusion criteria for patients with acute ischaemic stroke: 1) Patients with secondary ischaemic stroke caused by brain tumour traumatic brain injury cerebral parasitosis cerebral amyloid angiopathy arteritis and intracranial vascular malformation; 2) severe heart disease cardiac insufficiency liver dysfunction renal insufficiency respiratory failure malignant tumour gastrointestinal bleeding at the onset; 3) Psychiatric patients; 4)Pregnant and lactating women; 5) Patients with drug and alcohol abuse; Patients who are participating in other clinical trials. 2.2 Healthy control group exclusion criteria: 1) Psychiatric patients; 2) Pregnant and lactating women; (iii) Patients with drug abuse or alcohol abuse; (iv) Patients who are participating in other clinical trials; Patients who are participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Metabolic pathways related to differential metabolites in each group;Differential metabolites of Yin and Yang syndrome of ischemic stroke;

Countries

China

Contacts

Public ContactLijun Qiao

Guangdong Hospital of Traditional Chinese Medicine

qiaolijunwork@163.com13724105689

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026