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Clinical efficacy of low-intensity transcutaneous electrical auricular stimulation based on the auricular nail-vagus nerve link in persistent atrial fibrillation after radiofrequency ablation and the effect of NLRP3 inflammatory vesicles

Clinical efficacy of low-intensity transcutaneous electrical auricular stimulation based on the auricular nail-vagus nerve link in persistent atrial fibrillation after radiofrequency ablation and the effect of NLRP3 inflammatory vesicles

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000893
Enrollment
Unknown
Registered
2025-05-06
Start date
2024-02-05
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation

Interventions

treatment group:transcutaneous electrical stimulation of ear acupuncture points
control group:Conventional medication

Sponsors

The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with atrial fibrillation undergoing radiofrequency ablation less than 80 years of age

Exclusion criteria

Exclusion criteria: Patients with atrial fibrillation undergoing radiofrequency ablation who are 300ms) without permanent pacemaker implantation. Degree 2 and 3 atrioventricular (AV) block two-branch block and prolonged Degree I AV block (PR > 300ms)

Design outcomes

Primary

MeasureTime frame
Atrial fibrillation recurrence rate;NLRP3 inflammasome;Percentage of atrial fibrillation load;—

Secondary

MeasureTime frame
IL-18;IL-1ß;heart rate variability;TNF-a;—

Countries

China

Contacts

Public ContactZhou Xiaoxiong

The First Affiliated Hospital of Guangzhou University of Chinese Medicine

15918737859@163.com15918737859

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026