Senile Type 2 diabetes with Qi Deficiency and Blood Stasis
Conditions
Interventions
Treatment group:Liange Shuangshen Granule
Control group:Liange Shuangshen Granule Placebo
Sponsors
Eye Hospital China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age 60-85 years old; 2. Meet the diagnostic criteria for type 2 diabetes mellitus; 3. Meet the diagnostic criteria of stable coronary artery disease; 4. Meet the diagnostic criteria of qi deficiency and blood stasis syndrome; 5. Patients voluntarily participated in the trial and signed the informed consent form with a high degree of compliance and cooperative attitude.
Exclusion criteria
Exclusion criteria: 1. Patients with severe organic heart disease or heart failure (NYHA Class ? or above). 2. ALT and/or AST levels more than twice the upper reference limit or renal insufficiency (serum creatinine over 1.5 times the upper reference limit). 3. Patients with severe mental or intellectual or language disorders; patients with severe hematologic diseases; patients with malignancies; patients with disability. 4. Allergic to any Chinese or Western medicine used in this study. 5. Participating in or having participated in another drug trial within the past two months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycosylated hemoglobin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Seattle angina scale;TCM syndrome score;HOMA-IR;IL-6;Fasting insulin;Fasting blood glucose;METS-IR;CRP;TyG;Diabetes-specific quality of life scale;Ocular optical coherence tomography;Fasting C-peptide;Blood lipids;SOD; | — |
Countries
China
Contacts
Public ContactLi Cheng
EYE HOSPITAL CHINA ACADEMY OF CHINESE MEDICAL SCIENCES
Outcome results
None listed