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Study on the clinical and mechanism of the external application of the Si Cao Formula for the prevention and treatment of psoriasis

Study on the clinical and mechanism of the external application of the Si Cao Formula for the prevention and treatment of psoriasis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000872
Enrollment
Unknown
Registered
2025-04-28
Start date
2025-04-30
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis

Interventions

Experimental Group:1. Basic treatment (strengthening emollient and moisturising
reasonable bathing and cleaning of skin
avoiding triggering and aggravating factors
reasonable life and living
adhering to reasonable treatment)
2. Si Cao cream applied externally to the affected area twice a day for a total course of 8 weeks.
Control Group:1. Basic treatment (strengthening emollient and moisturising
2. calcipotriol applied externally to the affected area twice a day for a total course of 8 weeks.

Sponsors

Yueyang Hospital of Intergrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. It meets the western medical diagnostic criteria for psoriasis of the common type; 2 Skin lesions body surface area (BSA) <10% or PASI <10 points; 3. 18 years = age = 65 years gender is not limited; 4. Those who agreed to participate in this study and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. A history of intolerance to topical vitamin D3 derivatives or herbal topical treatments; 2. Other active skin diseases that may affect the assessment of the disease; 3. Previous treatment with etanercept infliximab ezekizumab adalimumab guselchizumab ustekinumab and skuticumab and discontinuation of the treatment = 14 40 52 64 72 days respectively 84 days and 108 days. Or have been treated with JAK inhibitors and the withdrawal time is =1 week; 4. Have received topical glucocorticoids phototherapy etc. within 2 weeks; 5. Are in the period of severe uncontrollable local or systemic acute or chronic infections; 6. Have a history of malignant tumours and patients with primary or secondary immunodeficiencies and hypersensitivity; 7. Are pregnant or breastfeeding women; 8. Have a history of alcohol drug or substance abuse; 9. Have a history or family history of severe psychiatric illness; 10. History or family history of severe mental illness; 10. Other reasons the investigator considers inappropriate for participation in this study.

Design outcomes

Primary

MeasureTime frame
relapse rate;

Secondary

MeasureTime frame
Treatment efficacy rate;Psoriasis Area and Severity Index(PASI);Visual analogue scale (VAS);Time of relapse;Dermatology Life Quality Index (DLQI);

Countries

China

Contacts

Public ContactBin Li

Yueyang Hospital of Intergrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine

18930568129@163.com+86 18930568129

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026