schizophrenia
Conditions
Interventions
stimulation:Electro-Acupuncture at Auricular Acupoint(transcutaneous auricular vagus nerve stimulation)
sham stimulation:Electrical stimulation of the skin at the auricular region (non-acupoint site without vagus nerve distribution
Sponsors
shanghai mental health center
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Meet the diagnostic criteria for schizophrenia in The Diagnostic and Statistical Manual of Mental Disorders fifth-edition (DSM-5); 2) 50 = age = 75 years; 3) The patient's antipsychotic medication and dosage had not been adjusted in the last two weeks; 4) Having cognitive impairment. score <26 on the MoCA scale; 5) is right-handed according to the Sharp Handedness Questionnaire screening; 6) have sufficient visual and auditory levels to ensure that the examinations and tests necessary for the study can be completed; 7) Sign a written informed consent form and agree to be enrolled in the trial according to the requirements of the study protocol.
Exclusion criteria
Exclusion criteria: 1. Presence of psychiatric disorders other than schizophrenia even if comorbid. 2. Participation in any other clinical trials within one months prior to this study. 3. Receipt of electroconvulsive therapy in the last one months. 4. New stroke incident within one month. 5. Severe impairments in vision hearing or language that could hinder completion of neuropsychological assessments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cognition;Memory attention and executive function; | — |
Secondary
| Measure | Time frame |
|---|---|
| clinical symptom; | — |
Countries
China
Contacts
Public Contactwei xiang
shanghai mental health center
Outcome results
None listed