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Basic and clinical evidence-based evaluation of acupuncture therapy regulating hypothalamus-pituitary-testicular axis function in the treatment of male reproductive dysfunction

Basic and clinical evidence-based evaluation of acupuncture therapy regulating hypothalamus-pituitary-testicular axis function in the treatment of male reproductive dysfunction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000857
Enrollment
Unknown
Registered
2025-04-27
Start date
2023-10-10
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male reproductive dysfunction

Interventions

control group 2:In the drug treatment group, 10 ml of L-carnitine oral solution was taken orally three times a day during meals in the morning, middle and evening, and treated with western medicine ea
Treatment group 1:Paravrontal three lines (CV4) Shenshu (BL23) Jingmen (GB25) and Taixi (K13) were used for acupuncture.
control group 1:Acupuncture was performed using non-acupoint 1 (FX1), non-acupoint 2 (FX2), and non-acupoint 3 (FX3).
Treatment group 2:Paravrontal Guanyuan (CV4), Zhongji (CV3), Zusanli (ST36)and Sanyinjiao (SP6) were used for acupuncture.

Sponsors

School of Traditional Chinese Medicine Ningxia Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
21 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1 .Meet the diagnostic criteria of asthenospermia oligospermia and azoospermia; 2. Aged 21-45 years (including 21 and 45 years). 3. Signed the informed consent form or signed by his immediate family members and volunteered to participate in the research of this project.

Exclusion criteria

Exclusion criteria: 1. Unconscious unable to express subjective discomfort symptoms mental patients. 2. Erectile dysfunction and abnormal ejaculation. 3. There are congenital malformation vas deferens obstruction testicular atrophy testicular volume is too small chromosome abnormality endocrine abnormality varicocele and reproductive tract inflammation. 4. Those who drink alcohol and take drugs that hinder spermatogenesis and sperm motility during treatment. 5. Positive seminal plasma antisperm antibody. 6. Complicated with serious diseases such as cardiovascular liver and kidney. 7. Spouse has infertility disease.

Design outcomes

Primary

MeasureTime frame
Anxiety condition;Semen quality;Metabonomic analysis ;Examination of reproductive hormone level ;Health status;

Secondary

MeasureTime frame
life quality;overall evaluation;Evaluation of expected value of acupuncture;Transcribed gene;

Countries

China

Contacts

Public ContactMa Huisheng

School of Traditional Chinese Medicine Ningxia Medical University

madoctor@163.com+86 137 0958 5190

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026