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A prospective cohort study on the improvement of ovarian reserve function and IVF-ET pregnancy outcomes in patients with DOR using the "Cultivating Soil and Nurturing Seeds" method

A prospective cohort study on the improvement of ovarian reserve function and IVF-ET pregnancy outcomes in patients with DOR using the "Cultivating Soil and Nurturing Seeds" method

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025000844
Enrollment
Unknown
Registered
2025-04-24
Start date
2024-10-10
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diminished Ovarian Reserve

Interventions

Control group:conventional western medicine treatment
Treatment group:Traditional Chinese medicine compound and conventional western medicine treatment

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
No minimum to 42 Years

Inclusion criteria

Inclusion criteria: 1.Age =42 years old; 2.Clinically diagnosed with DOR (referencing the Bologna criteria for DOR diagnosis: FSH between 10 U/L and 25 U/L AMH < 0.5-1.1 ng/mL or antral follicle count (AFC) < 4-6 on both ovaries; meeting any one of these criteria is sufficient. *Blood samples collected on days 2-5 of the menstrual cycle fasting venous blood); 3.Meets the TCM diagnostic criteria for "kidney deficiency syndrome"; 4.Participants are informed and voluntarily sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Severe gynecological or reproductive diseases; 2.Severe systemic diseases such as malignant tumors; 3.Significant abnormalities in liver or kidney function; 4.Failure to undergo IVF-ET within 3 months after the completion of TCM treatment.

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy rate;

Secondary

MeasureTime frame
Good quality embryo rate;Number of oocytes retrieved;TCM syndrome score;AFC;Rate of abortion;AMH;FSH;Biochemical pregnancy rate;Fetal malformation rate;

Countries

China

Contacts

Public ContactDong Li

Peking University Third Hospital

lidong6512@163.com15611908373

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026