Depressive Episode with Insufficient Symptoms
Conditions
Interventions
intervention group:Chinese herbal formula
Sponsors
The Hong Kong Jockey Club Charities Trust
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Age between 18 and 65; 2) Report the presence of 2 to 4 criterion symptoms of depression for 2 weeks or longer with at least 1 of the core symptoms (depressed mood or anhedonia); 3) Score between 5-14 in PHQ-9 in screening and baseline assessment; 4) Understand and be able to follow written and oral instructions in Chinese to complete the assessment questionnaire; 5) Willing and able to provide informed consent.
Exclusion criteria
Exclusion criteria: 1) Major Depressive Disorder (MDD) episode in past 6 months; 2) Present with severe symptoms of depression as indicated by PHQ-9 score >14; 3) History of active alcohol and/or substance abuse disorder in the past 12 months or history of psychiatric or psychotic disorders such as mania schizophrenia bipolar disorder post-traumatic stress disorder or obsessive-compulsive disorder; 4) History of major neurologic disorder (e.g. Parkinson disease Alzheimer disease or other dementia brain tumor seizure disorder or delirium episode); 5)Conditions that could make it difficult to conclusively determine that depressive symptoms were the result in some other conditions; 6)Current active suicidal or self-injurious potential necessitating immediate treatment; 7) History of serious chronic illness such as cancer stroke heart diseases end-stage liver and kidney diseases. 8) Pregnancy or lactation female; 9) Currently undergoing prescribed psychotropic medication psychotherapy or TCM treatment; 10) undergoing electroconvulsive therapy (ECT) in the past 12 months; 11) any psychiatric hospitalization in the past 2 years; 12) Allergic history to Chinese herbal drugs; 13) Concurrent participation in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient Health Questionnaire-9; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index;Hamilton depression rating scale;General Anxiety Disorder-7;Compliance rate;Perceived Stress Scale-10;Adverse events;Brief Resilience Scale; | — |
Countries
China
Contacts
Public ContactDr. YU Jucheng Danny
Hong Kong Baptist University
Outcome results
None listed