Multiple System Atrophy
Conditions
Interventions
Group B(health volunteer):no
Group A(MSA volunteer):no
Sponsors
Dongfang Hospital Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria of multiple system atrophy; (2) Age is over 30 years old and less than 80 years old gender is not limited; (3) Patients with good compliance to take medicine according to doctor's advice; (4) Other clinical researchers who did not participate in the study; (5) Voluntarily participate in this clinical trial and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Previous diagnosis of Alzheimer's disease and various secondary Parkinson's syndromes; (2) Neurological examination suggests that there is a systemic disease or other clear cause of brain atrophy or dementia; (3) Vertical rapid saccades were significantly slowed or vertical nuclear gaze palsy; (4) Evidence of local cerebral cortex damage such as aphasia heterotopia parietal lobe dysfunction; (5) moderate to severe head trauma hydrocephalus brain surgery or brain tumor history; (6) History of central nervous system infection metabolism and autoimmune diseases; (7) The presence of psychiatric disorders and hallucinations unrelated to the drug; (8) History of cataract glaucoma or other eye diseases; (9) A history of systemic diseases that may cause ocular symptoms affecting eye tracking; (10) Other factors affecting eye movement such as the use of antipsychotic drugs benzodiazepines or antidepressants within 72h; (11) Pregnant women with serious heart liver and kidney diseases who cannot complete the scale and related examinations; (12) claustrophobia; (13) Other conditions that the investigator considers unsuitable for participation in this study; (14) Refusal to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of multiple system atrophy symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of cognitive status;Multimodal magnetic resonance;Evaluation of the severity of fatigue;Eye movement tests;Parkinson symptom evaluation;Evaluation of non-motor symptoms in multiple system;Evaluation of mental and emotional status;Evaluation of TCM syndrome in brain marrow disease; | — |
Countries
China
Contacts
Public ContactCHEN-Zhigang/LI-Xiufang
Dongfang Hospital Beijing University of Chinese Medicine/Beijing University of Chinese Medicine
Outcome results
None listed