Diabetic Nephropathy
Conditions
Interventions
Sponsors
the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age =18 years old and =75 years old gender is not limited; (2) Complete demographic data; (3) Meet the diagnostic criteria of the Chinese Guidelines for the Prevention and Treatment of Diabetic Kidney Disease (2021 edition) the Chinese Guidelines for the Prevention and Treatment of Type 2 Diabetes (2020 edition) and the Guidelines for the Screening Diagnosis Prevention and Treatment of Chronic Kidney Disease (2017 edition); (4) The patient is informed of the study as approved by the ethics committee. Healthy population inclusion criteria (1) The patient has no known history of infection or risk factors including HIV hepatitis B or C virus syphilis etc. and no current systemic infection; (2) no obesity (body mass index >30) and/or diabetes no history of chronic kidney disease; Approved by the ethics committee patients were informed about the study.
Exclusion criteria
Exclusion criteria: (1) Infection or other acute disease within 1 month before this inclusion; (2) in a state of stress; (3) other unstable chronic diseases; (4) Have a history of acute and chronic gastrointestinal diseases including acute gastroenteritis functional gastrointestinal diseases inflammatory bowel disease celiac disease and other chronic gastrointestinal diseases; (5) Recent (=3 months) exposure to systemic antibiotics immunosuppressants chemotherapy history and chronic treatment history of proton pump inhibitors; (6) Pregnant or lactating women; (7) Recently (=3 months) participated in other drug clinical researchers; (8) People suffering from mental illness intellectual disability confusion etc. who cannot cooperate with the completion of relevant information collection; Subjects who met one or more of these criteria were excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| UACR;blood urea nitrogen;serum creatinine;Uric Acid;total cholesterol;Targeted metabolomics technology detection;FBG;eGFR;HbA1c;Non-targeted metabolomics technology detection;16S rDNA test;glycated serum protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| HDL-C;LDL-C;Triglyceride; | — |
Countries
CHINA
Contacts
Public ContactRONG YU
Hunan University of Traditional Chinese Medicine
Outcome results
None listed