poor ovarian response,POR
Conditions
Interventions
Acupuncture Group 2:IVF treatment
Superficial needling at sham points
Acupuncture Group 1:IVF treatment
Control group:IVF treatment
Sponsors
West China Second University Hospital
Eligibility
Sex/Gender
Female
Age
21 Years to 39 Years
Inclusion criteria
Inclusion criteria: (1) Aged 21 to <40 years; (2) Meet the diagnostic criteria for poor ovarian response (POR); (3) Voluntarily agree to participate in the trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) History of ovarian surgery, radiotherapy, or chemotherapy; (2) Severe primary systemic diseases (e.g., cardiovascular or cerebrovascular diseases, hepatic or renal dysfunction); (3) Chromosomal abnormalities; (4) Contraindications for acupuncture, including bleeding disorders or susceptibility to infections; severe allergies; skin ulcers or scars at acupuncture sites; or needle phobia; (5) Recurrent miscarriage (including biochemical pregnancies) with =2 episodes; (6) Recurrent implantation failure (RIF), defined as failure to achieve clinical pregnancy after at least 3 embryo transfer cycles or cumulative transfer of =10 high-quality embryos; (7) Uterine malformations (e.g., unicornuate uterus, bicornuate uterus, or untreated uterine septum) or untreated conditions impairing the endometrial cavity (e.g., adenomyosis, submucosal fibroids, intrauterine adhesions, uterine scarring); (8) Received acupuncture treatment within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of Oocytes Retrieved; | — |
Secondary
| Measure | Time frame |
|---|---|
| number of mature oocytes;2PN rate;Chemical Pregnancy;E2 level on HCG day;follicle-stimulating hormone;Usable embryo rate;clinical pregnancy;Ongoing pregnancy rate;Number of 2PN zygotes ;Endometrial thickness on HCG day;Antral Follicle Counting;Number of MII oocytes;Live birth rate;Cycle cancellation rate;Early pregnancy loss rate;anti-Mullerian hormone;High-quality embryo rate;Embryo implantation rate;Number of follicles =14mm on HCG day; | — |
Countries
China
Contacts
Public ContactJia Liu
West China Second University Hospital
Outcome results
None listed