Post-Stroke depression
Conditions
Sponsors
Shenzhen Hospital (Fu Tian) of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) A group of patients who met the definition of ischemic stroke as defined in the International Classification of Diseases Eleventh Edition (ICD-11) and whose depressive manifestations met the diagnostic criteria for depression in the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5); (2) Neuroimaging showing a first ischemic stroke with a disease duration of 1-6 months (recovery period); (3) Right-handedness as assessed by the Edinburgh Handedness Inventory (EHI); (4) Age greater than 18 years and less than 80 years; (5) Hamilton Depression Scale score (HAMD-17) = 8; (6) Not taking any medication related to the treatment of depression/taking a stable dose of depression medication; (7) Consciousness no significant communication difficulties and stable vital signs (as determined by the level of consciousness and language items of the National Instrument for Stroke Scale (NIHSS)); (7) Have not received acupuncture treatment in the previous 6 months.
Exclusion criteria
Exclusion criteria: (1) History of mental disorders drug abuse and addiction immediately prior to stroke; (2) Contraindications to acupuncture such as ulcers abscesses and skin infections at the site of needling; and (3) Patients with severe primary diseases of the circulatory system respiratory system digestive system urinary system endocrine system and hematopoietic system which cannot be controlled by conventional medication; (4) Planned surgery during the trial period. (4) Patients who are scheduled to undergo surgery during the trial; (5) Patients who are claustrophobic or in compliance with the trial. (5) Claustrophobia or other contraindications to functional magnetic resonance; and (6) Participation in other clinical trials within the last month; (7) Inability to give informed consent. (7) Inability to give informed consent; and (8) Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient Health Questionnaire - 9 Item Version;Hamilton Depression Scale-17 item; | — |
Secondary
| Measure | Time frame |
|---|---|
| Generalized Anxiety Disorder(GAD-7);Mao Treatment Expectancy Scale;Stroke specific Quality of Life Scale;Stroke Rehabilitation Self Efficacy Scale;Generalized Anxiety Disorder Scale-7;Improved Rankin Scale;national institute of health stroke scale; | — |
Countries
China
Contacts
Public ContactShaoyang Cui
Shenzhen Hospital (Fu Tian) of Guangzhou University of Chinese Medicine
Outcome results
None listed