acute respiratory distress syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients who met the diagnostic criteria of ARDS and received mechanical ventilation (ventilation mode VCV+PEEP); (2) aged 18 to 70 years old; (3) under the condition of the conscious and voluntary signing informed consent not to sign a consent form but by the legal representative or guardian shall;
Exclusion criteria
Exclusion criteria: 1. Allergic constitution or allergy to known ingredients of the drug; 2. The existence of chronic obstructive pulmonary disease long-term use of noninvasive ventilator breathing is expected to exist difficult weaning patients; 3. The existence of acute myocardial infarction or original acute exacerbation of chronic heart failure results in acute pulmonary edema and amalgamative infection to be involved with this study phase identification of 4 patients with disease. Combined with malignant tumors; 5. There are serious digestive system diseases such as acute digestive tract hemorrhage acute intestinal obstruction abdominal surgery abdominal interval syndrome) leads to the patients can't through bowel to test drugs; 6. There are serious diseases of the central nervous system (such as heavy or track craniocerebral injury acute massive cerebral infarction acute intracranial bleeding) patients with GCS score less than eight points; ? ? 7. Patients with pregnancy or lactation;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mechanical ventilation time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of ICU stay;inflammatory factor;C-reactive protein;white blood cell;28-day mortality rate;Index of oxygenation;Total hospital stay;procalcitonin;TCM syndrome score;Success rate of offline ventilator;APACHE? score;SIRS score; | — |
Countries
China
Contacts
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine