Acute Gastrointestinal Injury of Sepsis
Conditions
Interventions
control group:fluid infusion
multiple organ support therapy
Nutrition support therapy etc
treatment group:Add modified Xiangsha Liujunzi combined with Pingwei Powder on the basis of the control group
Sponsors
Luzhou Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.Expected length of stay in ICU is = 7 daysConform to the diagnostic standards 2.AGI (Acute Gastrointestinal Injury) score grade I - III 3.Over 18 years old gender unlimited 4.APACHE II score = 15 5.It is expected that patients will start enteral nutrition within 48 hours including oral nutritional supplements and through nasogastric tubes or nasojejunal tubesor gastrostomy/jejunostomy tubes. 6.The patient or their family member has given informed consent and is willing to accept this treatment plan.
Exclusion criteria
Exclusion criteria: 1.The expected length of stay in the ICU is less than 7 days 2.The primary disease is a gastrointestinal disorder such as peptic ulcer gastrointestinal bleeding gastric cancer mechanical intestinal obstruction etc 3.The Patient with AGI (Acute Gastrointestinal Injury) Grade IV 4.Woman during pregnancy 5.The patients with Severe cancer cachexiaor with opioid addiction 6.The patient's position is restricted and they are unable to cooperate with the ultrasound examination 7.The patient has a history of allergy to the traditional Chinese medicine drugs used in this study 8.Patients or their families who do not consent to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Enteral feeding calorie intake;The number of bowel sounds;antral contraction frequencyACF;Traditional Chinese Medicine (TCM) Syndrome Score;AcuteGastrointestinalinjury(AGI)classification;Gastric residual volume(GRV); | — |
Secondary
| Measure | Time frame |
|---|---|
| Procalcitonin (PCT);White blood cell count and percentage of neutrophils;Acute Physiology and Chronic Health Evaluation (APACHE-II);C-reactive protein (CRP);Sequential Organ Failure Assessment (SOFA) score; | — |
Countries
China
Contacts
Public ContactHe Hongcai
Luzhou Traditional Chinese Medicine Hospital
Outcome results
None listed